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The influence of a concrete form on the plastic response of smooth muscle tissue during fluid pressure testing. We tested the hypothesis that a form of a soft, flexible, permeable membrane causes a strain-related flow of fluid into the sample material and affects the resulting equilibrium values of its plastic properties. Porcine duodenal smooth muscle strips were wrapped around a rigid form that was either transparent or translucent and located inside a transparent plastic bag. Strips that were wrapped around a form filled with dry sand, and placed inside a rigid transparent form, served as controls. Plastic properties were determined from the pressure-strain relationships obtained from quasi-static tests. Tests were done under no tension, after partial unloading (1 N), and after the addition of tetrodotoxin (TTX; 1 microM). The results showed that 1) non-transparent form, or form containing sand, or form containing TTX significantly altered the pressure-strain relationships and increased the plateau values of mechanical and plastic properties, 2) the magnitude of the increase in plateau values did not depend on the shape of the form (rigid, non-rigid, or hollow), 3) these forms did not produce significant changes in the pressure-strain relationships of the cells wrapped around them, and 4) the plateau values of plastic properties of duodenal smooth muscle cells were almost 10 times smaller when a form was applied. These results, when taken together, support the hypothesis that a form, whether it is transparent or non-transparent, increases the plastic properties of soft, permeable tissue and decreases the magnitude of the changes in the plateau values of its mechanical properties.OAKLAND, Calif. -- Right-hander Yordano Ventura will stay in the minor leagues to start the season as he tries to continue recovering from a strained left biceps tendon. The 26-year-old right-hander will start his second stint with Triple-A Sacramento on Tuesday, manager Bob Melvin said. He said he felt the injury getting ready to pitch before the Oakland Athletics' season opener on Monday. He allowed three runs and four hits in five innings in that start. Yordano Ventura will be starting for Triple-A Sacramento this season. AP Photo/David Zalubowski "The first start was really good, but the next start was when it started a little bit of discomfort," Ventura said. "But they were in a lot of tight games, a lot of close games, so
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